Tanshindiol C - CAS 97465-71-9

Tanshindiol C protects macrophages from oxLDL induced foam cell formation via activation of Prdx1/ABCA1 signaling and that Prdx1 may be a novel target for therapeutic intervention of atherosclerosis.It possesses a unique anti-cancer activity whose mechanism involves the inhibition of EZH2 activity and would provide chemically valuable information for designing a new class of potent EZH2 inhibitors.

Sirtuin, Nrf2, LDL, Histone Methyltransferase

Immunology/Inflammation, Chromatin/Epigenetic, DNA Damage/DNA Repair, Metabolism

97385

C18H16O5

312.32

Cc1coc-2c1C(=O)C(=O)c1c-2ccc2c1CC[C@@H](O)[C@]2(C)O

-20°C

Ice Packs

Natural Product