Tanshinone IIA sulfonate sodium - CAS 69659-80-9

Tanshinone IIA sulfonate sodium (Tanshinone IIA sodium sulfonate) is a water-soluble derivative of tanshinone IIA extracted from Savia miltiorrhiza; a potent negative allosteric modulator of the human purinergic receptor P2X7. Tanshinone IIA sulfonate sodium (12.5 μM) inhibits hypoxia-induced PKG and PPAR-γ downregulation in PASMCs and distal pulmonary arteries of rats.

Calcium Channel, CaMK, Cytochromes P450

Membrane transporter/Ion channel, Metabolism, Neuroscience

69570

0.999

C19H17O6S·Na

396.39

[Na+].Cc1c2c(oc1S([O-])(=O)=O)-c1ccc3c(CCCC3(C)C)c1C(=O)C2=O

-20°C

Ice Packs

Natural Product