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TAS6417 - CAS 1661854-97-2

TAS6417 - CAS 1661854-97-2

MF-0016647-01

$97.31 USD
$97.31 USD
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Product Details

  • Bioactivity

    Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor that uniquely binds to the ATP binding site of the EGFR hinge region with an IC50 value of 1.1-8.0 nM.

  • Target

    Apoptosis, EGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis, Apoptosis

  • CAS Number

    1661755

  • Purity

    0.9971

  • Molecular Formula

    C23H20N6O

  • Molecular Weight

    396.44

  • SMILES

    CC1=C[C@@H](Cn2c1c(-c1cnc3ccccc3c1)c1c(N)ncnc21)NC(=O)C=C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound