Taspine - CAS 602-07-3

Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of HUVEC in a dose-dependent manner, it has shown meaningful angiogenesis activity. Taspine exhibits a dose-related cicatrizant effect and an ED50 of 0.375 mg/kg.

P2X Receptor, Bcl-2 Family, VEGFR, Akt, EGFR, MAPK, ERK

MAPK, PI3K/Akt/mTOR signaling, Tyrosine Kinase/Adaptors, Neuroscience, JAK/STAT signaling, Membrane transporter/Ion channel, Apoptosis, Angiogenesis, Cytoskeletal Signaling

602-07-3

C20H19NO6

369.37

COc1ccc2c3c1oc(=O)c1c(CCN(C)C)cc(OC)c(oc2=O)c31

-20°C

Ice Packs

Natural Product