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TAT-EE3 - CAS 2899218-49-4

TAT-EE3 - CAS 2899218-49-4

SKU:MF-0127439-01

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  • Bioactivity

    TAT-EE3 is a neuroprotective peptide that dissociates the interaction between TRPM2 and NMDARs. It inhibits the TRPM2-induced enhancement of NMDAR surface expression and current amplitude. TAT-EE3 protects neurons from ischemic damage both in vitro and in vivo, and is utilized for research on ischemic stroke.

  • Target

    Calcium Channel, iGluR, TRP/TRPV Channel

  • Related Pathways

    Neuroscience, Metabolism, Membrane transporter/Ion channel

  • CAS Number

    2899218-49-4

  • Molecular Formula

    C135H228N48O49S

  • Molecular Weight

    3339.61

  • SMILES

    [C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(O)=O)C(O)=O)=O)CCC(O)=O)=O)C)=O)CC(C)C)=O)C)=O)CC(C)C)=O)CCSC)=O)CCC(O)=O)=O)CCC(O)=O)=O)CO)=O)CO)=O)CC(O)=O)=O)[C@@H](C)O)=O)CC(O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCCNC(=N)N)=O)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC1=CC=C(O)C=C1)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Peptide