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Tat-βsyn-degron - CAS 2816095-52-8

Tat-βsyn-degron - CAS 2816095-52-8

SKU:MF-0127104-01

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  • Bioactivity

    Tat-βsyn-degron is an α-synuclein (α-synuclein) knockdown peptide that efficiently degrades the α-synuclein protein via the proteasome pathway. It effectively reduces α-synuclein protein levels in primary rat cortical neuron cultures. In Parkinson's mouse toxicity models, Tat-βsyn-degron alleviates neuronal damage and motor dysfunction induced by Parkinsonian toxins.

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    2816095-52-8

  • Molecular Formula

    C132H237N59O31

  • Molecular Weight

    3146.67

  • SMILES

    [C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(NCC(O)=O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)C(C)C)=O)CC(C)C)=O)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC2=CC=C(O)C=C2)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)[C@@H](C)O)=O)CCCCN)=O)CO)=O)=O)C(C)C)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Peptide