Tau-aggregation and neuroinflammation-IN-1 - CAS 2175953-98-5

Tau-aggregation and neuroinflammation-IN-1 is a potent inhibitor of tau protein aggregates, showing significant inhibitory activity against AcPHF6 and full-length tau protein aggregates. It has anti-inflammatory activity, reduces NO release, exhibits low cytotoxicity against LSP-stimulated BV2 cells, and reverses okadaic acid-induced memory impairment in rats.

NO Synthase, Microtubule Associated

Cytoskeletal Signaling, Immunology/Inflammation

2175850

>99.99%

C25H20N2O7

460.44

C[C@@]12C=3C(OC1=CC4=C(C2=O)C(C)=NN4C5=CC=C(C(O)=O)C=C5)=C(C(C)=O)C(O)=C(C)C3O

-20°C

Ice Packs

Small Compound