Tau ligand-1 - CAS 3063166-64-0

Tau ligand-1 (Compound 75) is a ligand of aggregated tau protein that can penetrate the blood-brain barrier. In tissues affected by Alzheimer's disease, progressive supranuclear palsy, corticobasal degeneration, and Pick's disease, Tau ligand-1 shows high affinity for aggregated tau protein, with equilibrium dissociation constants (KD) ranging from 1 to 3.8 nM. It holds potential as a positron emission tomography (PET) tracer for imaging studies of tau-related diseases within the central nervous system.

Microtubule Associated

Cytoskeletal Signaling

3063102

C17H16FN3O

297.327

FC1=NC(=CC=C1C2=CC=3C=CC=CC3N2)N4CCOCC4

-20°C

Ice Packs

Small Compound