Tauro-β-muricholic acid - CAS 25696-60-0

Tauro-β-muricholic acid (TβMCA), a trihydroxylated bile acid, serves as a competitive and reversible FXR antagonist (IC50 = 40 μM) and demonstrates antiapoptotic effects by preventing bile acid-induced hepatocellular apoptosis and maintaining mitochondrial membrane potential [1][2].

FXR, Apoptosis

Metabolism, Apoptosis

25696-60-0

C26H45NO7S

515.7

C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCC(NCCS(=O)(=O)O)=O)C)(CC4)[H])[H])([C@@H](O)[C@@H](O)[C@@]1(C[C@H](O)CC2)[H])[H])[H]

-20°C

Ice Packs

Natural Product