Taurodeoxycholic acid - CAS 516-50-7

Taurodeoxycholic acid (Taurodeoxychloic acid) is a bile acid taurine conjugate of deoxycholic acid, a human metabolite that stabilizes mitochondrial membranes and reduces the formation of free radicals.Taurodeoxycholic acid inhibits apoptosis by blocking calcium-mediated apoptotic pathways and by activation of caspase-12. Taurodeoxycholic acid has neuroprotective activity and has been used to study 3-nitropropionic acid-induced or stabilized hereditary Huntington's chorea (HD) .

PKA, Endogenous Metabolite, Apoptosis, NF-κB, PARP, Caspase, Calcium Channel, GPCR19

DNA Damage/DNA Repair, Tyrosine Kinase/Adaptors, Apoptosis, Metabolism, Proteases/Proteasome, GPCR/G Protein, NF-κB, Membrane transporter/Ion channel, Chromatin/Epigenetic

459

0.9922

C26H45NO6S

499.7

C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(C[C@@H]1O)[H])[H])(CC[C@@]2([C@@H](CCC(NCCS(=O)(=O)O)=O)C)[H])[H]

-20°C

Ice Packs

Natural Product