Taurohyodeoxycholic acid - CAS 2958-04-5

Taurohyodeoxycholic acid (THDCA) is a bile acid that plays a key role in regulating the hepatic inflammatory microenvironment.THDCA reduces the expression of TNF-α and IL-6 and inhibits the development of hepatocellular carcinoma (HCC) . It is able to inhibit non-alcoholic fatty liver disease and regulate bile acid metabolism in combination with astragalus polysaccharides: it reduces CD36 expression in the liver and decreases hepatic lipid accumulation by up-regulating CYP7B1 and down-regulating CYP7A1.

Interleukin, Endogenous Metabolite, Glutathione Peroxidase, Cytochromes P450, IL Receptor, COX, TNF

Neuroscience, Apoptosis, Immunology/Inflammation, Metabolism

2958-04-5

0.9938

C26H45NO6S

499.7

C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCC(NCCS(=O)(=O)O)=O)C)(CC4)[H])[H])(C[C@H](O)[C@@]1(C[C@H](O)CC2)[H])[H])[H]

-20°C

Ice Packs

Natural Product