Tauroursocholic Acid sodium salt - CAS 17515-36-5

Tauroursocholic acid (TUCA) is the taurine-conjugated derivative of ursocholic acid and serves as the 7β-hydroxy epimer of taurocholic acid (TCA) . Unlike TCA, TUCA does not inhibit HMG-CoA reductase or the cytochrome P450 (CYP) isoform CYP7A1, also known as cholesterol 7α-hydroxylase. Elevated bile levels of TUCA are observed in patients with biliary tract cancer compared to those with benign biliary conditions.

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17515-36-5

C26H44NNaO7S

537.69

O[C@@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC(NCCS(=O)([O-])=O)=O)([C@H](C[C@]2([H])[C@@]4([C@](C[C@@H](CC4)O)([H])C1)C)O)C.[Na+]

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