Tauroursodeoxycholate dihydrate - CAS 117609-50-4

Tauroursodeoxycholate (TUDCA , Taurolite) dihydrate is a water-soluble bile acid with endoplasmic reticulum stress inhibitory, mitochondrial stabilizing, and anti-apoptotic effects, which significantly reduces the expression of apoptotic molecules, such as Caspase-3 and Caspase-12, and inhibits ERK, reducing endoplasmic reticulum stress mediated cell death.

IRE1, ERK, JNK, Apoptosis, NF-κB, Caspase, Akt, ROS, Endogenous Metabolite

Cell Cycle/Checkpoint, PI3K/Akt/mTOR signaling, Apoptosis, Proteases/Proteasome, Immunology/Inflammation, NF-κB, MAPK, Cytoskeletal Signaling, Metabolism

117555

0.9982

C26H49NO8S

535.73

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NCCS(=O)(O)=O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])C[C@@H]3O)C.O.O

-20°C

Ice Packs

Natural Product