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Tazemetostat - CAS 1403254-99-8

Tazemetostat - CAS 1403254-99-8

SKU:MF-0014509-01

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  • Bioactivity

    Tazemetostat (EPZ6438) is a histone methyltransferase EZH2 inhibitor (IC50=11 nM) that is orally active, selective, and SAM-competitive. Tazemetostat exhibits antitumor activity and may be used for the treatment of epithelioid sarcoma/follicular lymphoma.

  • Target

    Apoptosis, Histone Methyltransferase

  • Related Pathways

    Chromatin/Epigenetic, Apoptosis

  • CAS Number

    1403147

  • Purity

    0.9984

  • Molecular Formula

    C34H44N4O4

  • Molecular Weight

    572.74

  • SMILES

    CCN(C1CCOCC1)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(CN2CCOCC2)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound