1 1

Molfinity

TBK1/IKKε-IN-4 - CAS 1381930-17-1

TBK1/IKKε-IN-4 - CAS 1381930-17-1

MF-0051079-01

$1,383.80 USD
$1,383.80 USD
Sale Sold out
Taxes included.
Size
View full details

Product Details

  • Bioactivity

    TBK1/IKKε-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKε, demonstrating IC50 values of 13 nM and 59 nM, respectively. This compound exhibits significantly reduced activity, by 100- to 1000-fold, against other protein kinases, such as PDK1, PI3K family members, and mTOR[1].

  • Target

    Others, IκB/IKK

  • Related Pathways

    Others, NF-κB

  • CAS Number

    1381912

  • Molecular Formula

    C28H35N7O4

  • Molecular Weight

    533.62

  • SMILES

    COc1ccc(cc1)-n1ncc2cnc(Nc3cc(OC)c(OC)c(OCCCN4CCN(C)CC4)c3)nc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound