TC-2559 difumarate - CAS 2454492-41-0

TC-2559 idifumarate is a CNS-selective, orally active α4β2 subtype of nicotinic acetylcholine receptor (nAChR) partial agonist with an EC50 of 0.18 μM. It exhibits selectivity for α4β2 receptors over α2β4, α4β4, and α3β4 receptors, with EC50s ranging from 10 to 30 μM. TC-2559 difumarate also demonstrates antinociceptive effects.

AChR, Others

Neuroscience, Others

2454451

C20H26N2O9

438.43

OC(/C=C/C(O)=O)=O.CNCC/C=C/C1=CN=CC(OCC)=C1.OC(/C=C/C(O)=O)=O

-20°C

Ice Packs

Small Compound