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Molfinity

TC-S 7009 - CAS 1422955-31-4

TC-S 7009 - CAS 1422955-31-4

MF-0034137-01

$57.84 USD
$57.84 USD
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Product Details

  • Bioactivity

    TC-S 7009 is a potent and selective HIF-2α inhibitor (Kd: 81 nM) with significantly higher affinity for HIF-2α than HIF-1α (Kd >> 5μM) . TC-S 7009 disrupts HIF-2α heterodimerization, reduces HIF-2α target gene expression, and diminishes DNA binding activity.

  • Target

    HIF/HIF Prolyl-Hydroxylase, HIF

  • Related Pathways

    Chromatin/Epigenetic, Angiogenesis, Metabolism

  • CAS Number

    1422920

  • Purity

    >99.99%

  • Molecular Formula

    C12H6ClFN4O3

  • Molecular Weight

    308.65

  • SMILES

    [O-][N+](=O)c1c(Nc2cc(F)cc(Cl)c2)ccc2nonc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound