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TCO-GK-PEG4-NHS ester - CAS 2307311-19-7
TCO-GK-PEG4-NHS ester - CAS 2307311-19-7
SKU:MF-0147774-01
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Product Details
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Bioactivity
TCO-GK-PEG4-NHS ester serves as an ADC linker, suitable for synthesizing [18F] AlF-NOTA-Tz-TCO-GK-2Rs15d, which demonstrates high affinity and immunoreactivity to HER2 [1]. This compound is a click chemistry reagent containing a TCO group that can engage in an inverse electron demand Diels-Alder reaction (iEDDA) with Tetrazine-containing molecules.
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Target
ADC Linker
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Related Pathways
Antibody-drug Conjugate/ADC Related
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CAS Number
2307311-19-7
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Molecular Formula
C33H52N4O14
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Molecular Weight
728.78
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SMILES
O(C(CCOCCOCCOCCOCCC(NCCCC[C@H](NC(CNC(OC1CCCC=CCC1)=O)=O)C(O)=O)=O)=O)N2C(=O)CCC2=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound