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TCO-PEG3-Glu-Val-Cit-PABC-MMAF - CAS 2862795-63-7
TCO-PEG3-Glu-Val-Cit-PABC-MMAF - CAS 2862795-63-7
SKU:MF-0121998-01
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Product Details
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Bioactivity
TCO-PEG3-Glu-Val-Cit-PABC-MMAF is a linker-drug conjugate composed of a TCO moiety for click chemistry, a PEG linker, a cleavable Glu-Val-Cit bond, a PABC group, and the cytotoxic molecule MMAF. This compound is utilized in the synthesis of dual-drug ADCs.
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Target
Drug-Linker Conjugates for ADC
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Related Pathways
Antibody-drug Conjugate/ADC Related
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CAS Number
2862795-63-7
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Molecular Formula
C80H126N12O22
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Molecular Weight
1607.92
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SMILES
O=C(OC1CCC=CCCC1)NCCOCCOCCOCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC2=CC=C(C=C2)COC(=O)N(C)C(C(=O)NC(C(=O)N(C)C(C(OC)CC(=O)N3CCCC3C(OC)C(C(=O)NC(C(=O)O)CC=4C=CC=CC4)C)C(C)CC)C(C)C)C(C)C)CCCNC(=O)N)C(C)C)CCC(=O)O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound