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TCS 2314 - CAS 317353-73-4
TCS 2314 - CAS 317353-73-4
SKU:MF-0034149
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$3,761.82 USD
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Product Details
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Bioactivity
TCS 2314 (compound 3) is a potent and selective VLA-4 (α4β1 integrin; CD49d/CD29) antagonist with an IC50 of 4.4 nM. It exhibits high plasma clearance and low oral bioavailability in rats, making it suitable for asthma research.
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Target
Integrin
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Related Pathways
Cytoskeletal Signaling
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CAS Number
317276
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Molecular Formula
C28H34N4O6
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Molecular Weight
522.59
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SMILES
C(=O)([C@H]1N(C(CC2=CC=C(NC(NC3=C(C)C=CC=C3)=O)C=C2)=O)CCOC1)N4CCC(CC(O)=O)CC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound