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Molfinity

TCS 2314 - CAS 317353-73-4

TCS 2314 - CAS 317353-73-4

SKU:MF-0034149

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  • Bioactivity

    TCS 2314 (compound 3) is a potent and selective VLA-4 (α4β1 integrin; CD49d/CD29) antagonist with an IC50 of 4.4 nM. It exhibits high plasma clearance and low oral bioavailability in rats, making it suitable for asthma research.

  • Target

    Integrin

  • Related Pathways

    Cytoskeletal Signaling

  • CAS Number

    317276

  • Molecular Formula

    C28H34N4O6

  • Molecular Weight

    522.59

  • SMILES

    C(=O)([C@H]1N(C(CC2=CC=C(NC(NC3=C(C)C=CC=C3)=O)C=C2)=O)CCOC1)N4CCC(CC(O)=O)CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound