TDRL-X80 - CAS 292065-64-6

TDRL-X80 is a potent inhibitor of the pigmented dry skin protein (XPA), inhibiting the DNA binding activity of XPA. It acts on single, double, and cisplatin-damaged DNA with IC50 values of 18, 20, and 29 μM in fluorescence polarization (FP) assays and 21, 39, and 28 μM in ELISA assays.

DNA/RNA Synthesis, Others

Others, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

291995

C23H15ClN2O6

450.83

CC1=NN(C(=O)C\1=C/C1=CC=C(O1)C1=CC(C(O)=O)=C(Cl)C=C1)C1=CC=CC(=C1)C(O)=O

-20°C

Ice Packs

Small Compound