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TE-11 - CAS 160488-11-9
TE-11 - CAS 160488-11-9
SKU:MF-0115176-01
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Product Details
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Bioactivity
TE-11 is a MIF tautomerase inhibitor with an IC50 of 5.63 μM. This compound can alleviate Crohn's-like colitis, reduce MIF-induced migration of eosinophils and neutrophils, and prevent M1 polarization and associated metabolic reprogramming.
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Target
MIF
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Related Pathways
Immunology/Inflammation
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CAS Number
160468
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Molecular Formula
C16H13NO
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Molecular Weight
235.28
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SMILES
O=C\1C=2C(CC/C1=C\C3=CC=CC=N3)=CC=CC2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound