Tebanicline tosylate - CAS 198283-74-8

Tebanicline is a potent synthetic nicotinic (non-opioid) analgesic drug. It was developed as a less toxic analogue of the potent poison dart frog-derived compound epibatidine. Like epibatidine, tebanicline showed potent analgesic activity against neuropathic pain in both animal and human trials, but with far less toxicity than its parent compound. It acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes.

AChR, Others

Neuroscience, Others

198201

C16H19ClN2O4S

370.85

S(=O)(=O)(O)C1=CC=C(C)C=C1.O(C[C@H]1CCN1)C=2C=CC(Cl)=NC2

-20°C

Ice Packs

Small Compound