Skip to product information
1 of 1

Molfinity

Tefinostat - CAS 914382-60-8

Tefinostat - CAS 914382-60-8

SKU:MF-0012292-01

Regular price $103.81 USD
Regular price $63.05 USD Sale price $103.81 USD
Sale Sold out
Taxes included.
Size
Quantity
View full details
  • Bioactivity

    Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor that is cleaved to the active acid CHR-2847 by intracellular esterase human carboxylesterase-1 (hCE-1) . Tefinostat exhibits antitumor activity and can be used in the study of leukemia and advanced hematologic malignancies.

  • Target

    Apoptosis, HDAC

  • Related Pathways

    Chromatin/Epigenetic, Apoptosis, DNA Damage/DNA Repair

  • CAS Number

    914382-60-8

  • Purity

    0.9983

  • Molecular Formula

    C28H37N3O5

  • Molecular Weight

    495.61

  • SMILES

    ONC(=O)CCCCCCC(=O)Nc1ccc(CN[C@H](C(=O)OC2CCCC2)c2ccccc2)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound