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Tefinostat - CAS 914382-60-8
Tefinostat - CAS 914382-60-8
SKU:MF-0012292-01
Regular price
$103.81 USD
Regular price
$63.05 USD
Sale price
$103.81 USD
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Product Details
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Bioactivity
Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor that is cleaved to the active acid CHR-2847 by intracellular esterase human carboxylesterase-1 (hCE-1) . Tefinostat exhibits antitumor activity and can be used in the study of leukemia and advanced hematologic malignancies.
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Target
Apoptosis, HDAC
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Related Pathways
Chromatin/Epigenetic, Apoptosis, DNA Damage/DNA Repair
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CAS Number
914382-60-8
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Purity
0.9983
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Molecular Formula
C28H37N3O5
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Molecular Weight
495.61
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SMILES
ONC(=O)CCCCCCC(=O)Nc1ccc(CN[C@H](C(=O)OC2CCCC2)c2ccccc2)cc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound