Temozolomide - CAS 85622-93-1

Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity. Temozolomide has antitumor activity and antiangiogenic activity, and also induces apoptosis and autophagy. Temozolomide is stable under acidic conditions and hydrolyzes under neutral or slightly alkaline conditions.

DNA Alkylator/Crosslinker, Apoptosis, Autophagy, DNA/RNA Synthesis

Cell Cycle/Checkpoint, Autophagy, Apoptosis, DNA Damage/DNA Repair

85528

0.9987

C6H6N6O2

194.15

CN1N=NC2=C(N=CN2C1=O)C(N)=O

-20°C

Ice Packs

Small Compound