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Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium - CAS 2611373-74-9
Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium - CAS 2611373-74-9
SKU:MF-0038032-01
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Product Details
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Bioactivity
Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) exhibits a prolonged half-life (t1/2) compared to tenofovir in human liver microsomes, demonstrates potent in vitro anti-HIV activity, and improves in vivo pharmacokinetic properties.
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Target
HIV Protease, Others
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Related Pathways
Others, Microbiology/Virology, Proteases/Proteasome
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CAS Number
2611290
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Molecular Formula
C29H55N6O5PSi
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Molecular Weight
626.855
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SMILES
N.C[C@H](Cn1cnc2c(N)ncnc12)OCP(O)(=O)OCCCOCCCCCCCCCCCCC#C[Si](C)(C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound