Terminal deoxyribonucleotidyltransferase - CAS 9027-67-2

Terminal deoxyribonucleotidyltransferase (TdT) catalyzes the addition of deoxyribonucleotide triphosphates to the 3' hydroxyl terminus of a DNA chain and introduces N regions at gene segment junctions during V (D) J recombination. It is expressed in immature, pre-B, and pre-T lymphocytes, as well as in acute lymphoblastic leukemia/lymphoma cells.

DNA/RNA Synthesis

Cell Cycle/Checkpoint, DNA Damage/DNA Repair

9027-67-2

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