Termitomycamide B - CAS 1254277-89-8

Endoplasmic reticulum (ER) stress, caused by accumulation of misfolded proteins and a disruption of calcium homeostasis, has been linked to several neuronal diseases including, Parkinson's, Alzheimer's, and prion diseases. A screen for protective activity against ER stress-dependent cell death identified termitomycamides, extracts from the fruiting bodies of T. titanicus, a notably large edible mushroom that is cultivated symbiotically in the nests of termites Termitomycamide B is a fatty acid isolated from T. titanicus that at a dose of 0.1 μg/ml protects against ER stress-dependent cell death in Neuro2a cells induced by tunicamycin.

Others, GPCR

Others, GPCR/G Protein, Endocrinology/Hormones

1254180

C28H40N2O2

436.63

C(CNC(CCCCCCC/C=C\C/C=C\CCCCC)=O)(=O)C1=CC=2C(N1)=CC=CC2

-20°C

Ice Packs

Small Compound