Terpestacin - CAS 146436-22-8

Terpestacin, found in Phoma exigua var. heteromorpha, binds to UQCRB to inhibit the production of mitochondrial ROS and HIF-1α. It suppresses tumor angiogenesis in FM3A breast cancer cell xenograft mouse models and possesses both antitumor activity and phytotoxicity.

Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase

Metabolism, NF-κB, Chromatin/Epigenetic, Immunology/Inflammation

146436-22-8

-20°C

Ice Packs

Natural Product