Tert-Butyl (10-aminodecyl) carbamate - CAS 216961-61-4

Tert-Butyl (10-aminodecyl) carbamate (1-Boc-1,10-diaminodecane) serves as a PROTAC linker in the synthesis of PROTACs and other binding applications. This compound contains an alkane chain with a terminal amine and a Boc-protected amino group. The amine group can react with carboxylic acids, activated NHS esters, and carbonyls (ketones and aldehydes) . The Boc group can be removed under mild acidic conditions to yield a free amine.

PROTAC Linker

PROTAC

216896

C15H32N2O2

272.427

O=C(OC(C)(C)C)NCCCCCCCCCCN

-20°C

Ice Packs

PROTAC