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Tesevatinib - CAS 781613-23-8

Tesevatinib - CAS 781613-23-8

MF-0018068-01

$113.56 USD
$113.56 USD
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Product Details

  • Bioactivity

    Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor with IC50 values ​​of 0.3, 16, 1.5, 8.7, and 1.4 nM for EGFR, ErbB2, KDR, Flt4, and EphB4.

  • Target

    VEGFR, FLT, EGFR, Ephrin Receptor, Src

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

  • CAS Number

    781582

  • Purity

    0.9866

  • Molecular Formula

    C24H25Cl2FN4O2

  • Molecular Weight

    491.39

  • SMILES

    COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(C)C[C@H]2C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound