Tetradifon - CAS 116-29-0

Tetradifon is a broad-spectrum organochlorine acaricide insecticide and a potent inhibitor of the mitochondrial oligomycin sensitivity conferring protein (OSCP), a subunit of ATP synthase. Tetradifon is utilized for controlling a variety of mite pests and inhibiting energy-related mitochondrial activities including ADP-stimulated respiration and ATPase activity with an IC50 range of 4.5-27 nmoL/mg mitochondrial protein; it exerts oligomycin-like effects by inhibiting oxidative phosphorylation, inducing significant oxidative stress, and interfering with bone metabolism, making it a compound of interest for researching mitochondrial function, bone remodeling mechanisms, and nephrotoxicity.

ATPase, Parasite

Membrane transporter/Ion channel, Microbiology/Virology

87

0.9984

C12H6Cl4O2S

356.05

O=S(=O)(C1=CC=C(Cl)C=C1)C2=CC(Cl)=C(Cl)C=C2Cl

-20°C

Ice Packs

Small Compound