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Tetrafluoro-thalidomide - CAS 179033-21-7
Tetrafluoro-thalidomide - CAS 179033-21-7
SKU:MF-0114874-01
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Product Details
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Bioactivity
Tetrafluoro-thalidomide is a fluorinated analog of thalidomide. It acts as an activator of E3 ligase enzymes, facilitating the ubiquitination of proteins for subsequent proteolysis. The structure of tetrafluoro-thalidomide can be further derivatized through fluorine substitution.
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Target
Ligand for E3 Ligase
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Related Pathways
PROTAC
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CAS Number
179005
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Molecular Formula
C13H6F4N2O4
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Molecular Weight
330.191
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SMILES
O=C1C=2C(F)=C(F)C(F)=C(F)C2C(=O)N1C3C(=O)NC(=O)CC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC