Tetrahydrouridine - CAS 18771-50-1

Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator. It can be used in cancer treatment to make tumor cells more sensitive to radiation therapy. THU is a competitive cytidine deaminase (CDA) inhibitor that inhibits deamination in the catabolism of cytotoxic deoxycytidine analogs such as ara-C and Gemcitabine.

Others, DNA/RNA Synthesis, DNA Methyltransferase

Others, Chromatin/Epigenetic, DNA Damage/DNA Repair, Cell Cycle/Checkpoint

18720

C9H16N2O6

248.23

O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(O)CC2

-20°C

Ice Packs

Small Compound