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Molfinity

TFCA - CAS 895700-18-2

TFCA - CAS 895700-18-2

MF-0118225-01

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Product Details

  • Bioactivity

    TFCA is a liver X receptor α (LXRα) antagonist. It inhibits the coactivation of ligand-activated LXRα and suppresses the transcriptional expression of downstream target genes involved in fatty acid synthesis. By selectively inhibiting LXRα in the liver, TFCA reduces ligand-induced lipogenesis and fatty liver.

  • Target

    Liver X Receptor

  • Related Pathways

    Metabolism

  • CAS Number

    895680

  • Molecular Formula

    C18H16F3NO3

  • Molecular Weight

    351.32

  • SMILES

    O=C(C=CC1=CC=C(OC)C(OC)=C1)NC2=CC=C(C=C2)C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound