TFLLRNPNDK-NH2 - CAS 145229-90-9

TFLLRNPNDK-NH2 is a biologically active peptide and a thrombin receptor activating peptide (TRAP) . As a PAR-1 agonist, it reversibly binds to PAR-1, mimicking the 'tethered ligand' created by thrombin through proteolytic substrate cleavage. It also induces increased liquid and protein permeability, similar to thrombin's effect.

Thrombin

Proteases/Proteasome

145130

C54H89N17O15

1216.39

C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H]([C@@H](C)O)N)=O)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)CC(N)=O)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N)=O)=O)CC(O)=O)=O)CC(N)=O)=O)CCC2

-20°C

Ice Packs

Peptide