TG11-77 free base - CAS 2490544-33-5

TG11-77 free base is a novel, Potent, Selective, Water Soluble, Brain-Permeable EP2 Receptor Antagonist. TG11-77 free base has a Schild KB of 9.7 nM on EP2, a water solubility of 2.5 mM, a brain-to-plasma ratio of 0.4, and a plasma half-life of 2.4 h in mice. TG11-77 free base are representative second generation EP2 antagonists with improved pharmacodynamic and pharmacokinetic properties.

Others

Others

2490506

C23H24N6O

400.48

C(CNC(=O)C=1C=NC(NC2=CC(C)=CC(C)=N2)=NC1)C=3C=4C(NC3C)=CC=CC4

-20°C

Ice Packs

Small Compound