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TGFβRI-IN-4 - CAS 2421135-03-5

TGFβRI-IN-4 - CAS 2421135-03-5

MF-0141399-01

$1,927.85 USD
$1,927.85 USD
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Product Details

  • Bioactivity

    TGFβRI-IN-4 is a potent, orally active TGFβ receptor type I kinase (TGFβRI) inhibitor that targets ALK5 (IC50: 44 nM) and NIH3T3 (IC50: 42.5 nM), inhibiting tumor growth and weight in a xenograft tumor model.

  • Target

    TGF-beta/Smad, Others

  • Related Pathways

    Others, Stem Cells

  • CAS Number

    2421135-03-5

  • Molecular Formula

    C23H25F2N5O2

  • Molecular Weight

    441.47

  • SMILES

    O(C=1C(=NN(C1)C2CC2)C3CC(F)(F)C3)C=4C=C(NC=5C=C(C(C)(C)O)N=CC5)N=CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound