Molfinity

TGF-βRI inhibitor 3 - CAS 666729-57-3

SKU:MF-0113631-01

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Product Details

Bioactivity
TGF-βRI inhibitor 3 (Compound 9ac) is a selective inhibitor of TGF-β that effectively suppresses the TGF-β signaling pathway. It exhibits IC50 values of 13 μM for c-Src kinase and 0.63 μM for ALK5 kinase.
Target
TGF-beta/Smad, Src, ALK
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Stem Cells
CAS Number
666669
Molecular Formula
C21H21NO4
Molecular Weight
351.396
SMILES
O=C(C=1C=C(C(=CC1OC=2C=CN=C3C=C(OC)C(OC)=CC32)C)C)C
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound