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TGFBR1-IN-2 - CAS 733806-89-8
TGFBR1-IN-2 - CAS 733806-89-8
SKU:MF-0112191-01
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Product Details
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Bioactivity
TGFBR1-IN-2 (Compound AQA) is a TGFBR1 inhibitor (KD: 0.01 μM) and antimicrobial agent. It serves as a substrate for cytochrome P450. The compound contains a pyridyl-6-methyl group, essential for inhibiting Mycobacterium tuberculosis, and effectively inhibits non-replicating and persistent strains of this bacterium.
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Target
Cytochromes P450, Antibacterial, TGF-beta/Smad
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Related Pathways
Microbiology/Virology, Stem Cells, Metabolism
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CAS Number
733709
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Molecular Formula
C19H15N5
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Molecular Weight
313.36
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SMILES
N=1C=CC(=CC1)NC=2N=C(N=C3C=CC=CC32)C=4N=C(C=CC4)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound