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TH1217 - CAS 1862212-48-3

TH1217 - CAS 1862212-48-3

SKU:MF-0014453-01

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  • Bioactivity

    TH1217, a potent and selective inhibitor of dCTPase pyrophosphatase 1 (dCTPase), demonstrates an IC50 value of 47 nM. It amplifies the cytotoxic impact of cytidine analogues on leukemia cells and exhibits potential against COVID-19 by modulating SARS-CoV-2 interactors.

  • Target

    Others, SARS-CoV

  • Related Pathways

    Others, Microbiology/Virology

  • CAS Number

    1862161

  • Purity

    0.9964

  • Molecular Formula

    C20H17BCl2N4O6

  • Molecular Weight

    491.09

  • SMILES

    Cc1nc2c(c(Cl)c(Cl)cc2n1Cc1ccc(cc1)[B-]12OC(=O)C[N+]1(C)CC(=O)O2)[N+]([O-])=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound