1 1

Molfinity

TH1760 - CAS 2567914-01-4

TH1760 - CAS 2567914-01-4

MF-0119598-01

$47.38 USD
$47.38 USD
Sale Sold out
Taxes included.
Size
View full details

Product Details

  • Bioactivity

    TH1760 (MKB) is an inhibitor of NUDIX-type 15 (NUDT15, IC50= 25 nM) . TH1760 can sensitize cells to 6-thioguanine by increasing the accumulation of 6-thio- (d) GTP in nucleic acids. TH1760 can enhance the anti-leukemia effect of thiopurine.

  • Target

    Others, DNA/RNA Synthesis, NUDIX hydrolase

  • Related Pathways

    Metabolism, DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others

  • CAS Number

    2567914-01-4

  • Purity

    0.9731

  • Molecular Formula

    C20H18N4O5S

  • Molecular Weight

    426.45

  • SMILES

    S(=O)(=O)(C=1C=C2C(=CC1)NC(=O)O2)N3CCN(C(=O)C=4C=C5C(=CC4)NC=C5)CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound