TH9028 - CAS 2379556-15-5

TH9028 is an inhibitor of MTHFD2, featuring an IC50 value of 11 nM. It demonstrates specific inhibitory activity with IC50 values of 7.97 nM, 27 nM, and 0.5 nM against hMTHFD2, MTHFD2L, and MTHFD1, respectively.

Dehydrogenase

Metabolism

2379536

C16H18N12O5

458.39

N(C(NC1=C(N)NC(N)=NC1=O)=O)C=2C=CC(C(N[C@@H](CCC=3NN=NN3)C(O)=O)=O)=NC2

-20°C

Ice Packs

Small Compound