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Thalidomide-4-Br,7-F - CAS 2740657-30-9
Thalidomide-4-Br,7-F - CAS 2740657-30-9
SKU:MF-0114239-01
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Product Details
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Bioactivity
Thalidomide-4-Br,7-F is an E3 ligase activator that contains both a bromine and a fluorine atom. E3 ligases are proteins that tag other proteins with ubiquitin to facilitate their degradation via proteolysis. The two halogens can be substituted for further derivatization.
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Target
Ligand for E3 Ligase
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Related Pathways
PROTAC
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CAS Number
2740618
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Molecular Formula
C13H8BrFN2O4
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Molecular Weight
355.116
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SMILES
O=C1NC(=O)C(N2C(=O)C=3C(F)=CC=C(Br)C3C2=O)CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC