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Thalidomide-4-carbaldehyde - CAS 2369068-46-0

Thalidomide-4-carbaldehyde - CAS 2369068-46-0

MF-0114404-01

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Product Details

  • Bioactivity

    Thalidomide-4-carbaldehyde is a thalidomide analogue that contains an aldehyde group. Thalidomide recruits E3 ligases for ubiquitination, leading to proteolysis of target proteins. The aldehyde is highly reactive with amine nucleophiles via reactions like reductive amination.

  • Target

    Ligand for E3 Ligase

  • Related Pathways

    PROTAC

  • CAS Number

    2369022

  • Molecular Formula

    C14H10N2O5

  • Molecular Weight

    286.24

  • SMILES

    O=CC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC