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Thalidomide-4-F,5-Br - CAS 2740657-28-5
Thalidomide-4-F,5-Br - CAS 2740657-28-5
SKU:MF-0114375-01
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Product Details
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Bioactivity
Thalidomide-4-F,5-Br is an analog of Thalidomide. It recruits E3 ligase for ubiquitination, which is followed by proteolysis of the target protein. This molecule can be derivatized through substitution with either fluorine or bromine.
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Target
Ligand for E3 Ligase
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Related Pathways
PROTAC
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CAS Number
2740624
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Molecular Formula
C13H8BrFN2O4
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Molecular Weight
355.116
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SMILES
O=C1NC(=O)C(N2C(=O)C3=CC=C(Br)C(F)=C3C2=O)CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC