Thalidomide 4-fluoride - CAS 835616-60-9

Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.

Autophagy, Apoptosis, IRAK, Ligand for E3 Ligase

Apoptosis, Immunology/Inflammation, NF-κB, Autophagy, PROTAC

835547

0.9912

C13H9FN2O4

276.22

O=C1N(C(=O)C=2C1=CC=CC2F)C3C(=O)NC(=O)CC3

-20°C

Ice Packs

PROTAC