Thalidomide-4-OH-C11-OH - CAS 3071165-50-6

Thalidomide-4-OH-C11-OH is a conjugate of an E3 ligase ligand and a linker (E3LigaseLigand-Linker Conjugates), comprising Thalidomide-4-OH and the corresponding linker. Thalidomide-4-OH-C11-OH acts as a Cereblon ligand to recruit CRBN protein and serves as a key intermediate for synthesizing complete PROTAC molecules, such as PROTAC GPX4 degrader-4.

E3 Ligase Ligand-Linker Conjugate

PROTAC

3071109

C24H32N2O6

444.52

O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCCCCCCCCCCO)C3C2=O)CC1

-20°C

Ice Packs

PROTAC