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Thalidomide-5-carbaldehyde - CAS 1447701-63-4

Thalidomide-5-carbaldehyde - CAS 1447701-63-4

MF-0114222-01

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Product Details

  • Bioactivity

    Thalidomide-5-carbaldehyde is an aldehyde-containing analogue of Thalidomide. Thalidomide recruits E3 ligase for ubiquitination, leading to proteolysis of target proteins. The aldehyde group exhibits high reactivity towards amine nucleophiles through reactions such as reductive amination.

  • Target

    Ligand for E3 Ligase

  • Related Pathways

    PROTAC

  • CAS Number

    1447634

  • Molecular Formula

    C14H10N2O5

  • Molecular Weight

    286.24

  • SMILES

    O=CC1=CC=C2C(=O)N(C(=O)C2=C1)C3C(=O)NC(=O)CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC