Thalidomide 5-fluoride - CAS 835616-61-0

Thalidomide 5-fluoride (H-Isoindole-1,3 (2H) -dione, 2- (2,6-dioxo-3-piperidinyl) -5-fluoro-) is a thalidomide-based Cereblon ligand that binds to the IRAK4 protein ligand via a linker to form PROTACIRAK4 degrader-1.

Autophagy, Ligand for E3 Ligase, Apoptosis

PROTAC, Autophagy, Apoptosis

835555

0.9862

C13H9FN2O4

276.22

O=C1N(C(=O)C=2C1=CC(F)=CC2)C3C(=O)NC(=O)CC3

-20°C

Ice Packs

PROTAC